I understand the new upgrade may effect HEM.

Here's a fix from HEM

Update HM1: http://www.holdemmanager.com/Downloa..._20Mar2011.exe

Note the HM1 update will perform a big database update when you run it.
So ignore any "not responding" error but wait for the program to unfreeze and the database update to finish. Make sure you have enough of free diskspace.
If you have a 40 GB database--> the database update would like 10 GB of free space (to use temporarily).
If you see a "

HM2: http://www.holdemmanager.com/Downloa... (even more recent build)

For HM1: easiest to do: downgrade to
FAQ - Hold'em Manager Poker Tracking Software :: Download Links For Past Builds

If you're asked for a serial number when you upgrade here's how to find it

Start HoldemManager--> click HELP--> SHOW SERIAL--> copy it.
Upgrade again--> and activate it again with the same serial.